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An inappropriate lifestyle and nutritional habits such as high fat, high calorie food intake and quality of drinking water can change sperm parameters. Despite the fact that there are different and sometimes contradictory beliefs about the suitable temperature for drinking water, unfortunately, there is not much proven evidence. There are some long-term adverse effects of cold-water intake like liver, gastrointestinal and other internal organ damages and dysfunction.  Regarding the high consumption of ice-cold water as a beverage and its probable role for infertility based on some trivial evidence and clinical senses, evaluation of the effects of ice-cold water drinking on reproductive system is noteworthy. Therefore, the main aim of this study is to assess the effect of long-term drinking of ice-cold water on the sperm count, morphology and motility and testis histology. Twenty-four male Wistar rats randomly divided into four groups (n = 6):  Intervention groups that used ice-cold water (4^oC) for two months (CW2M), three months (CW3M), two months ice-cold water and then one-month room-temperature water (CW2M + 1MRW), and control group that used room-temperature water. Spermatogram and histology of testis were assessed. Ice-cold water drink for the long run, reduced sperm count and sperm progressive motility; increased the percentage of non-motile sperm; changed normal morphology of sperm and destroyed Sertoli and Leydig cells. In conclusion, long-term ice-cold water drinking ought to be noxious for testis function and structure.

Intermediate hyperglycemia (Prediabetes) is a type of metabolic disorder with slight increase in the blood glucose levels from the normal but not reaching up to the level of diabetes. It is associated with many micro-vascular as well as macro-vascular complications. Abundance of Unani medicines are known for anti-hyperlipidemic activity, among them is Maghz-e-Jamun (Eugenia jambolana). The present study was to evaluate the anti-hyperlipidemic effect of Maghz-e-Jamun (Eugenia jambolana) in intermediate hyperglycemia. Patients diagnosed with prediabetes as per ADA criteria were randomly divided in two groups- group A was supplemented with 4.5g powder /day jamun seed powder in the form of capsules and group B was given placebo capsules. Lipid profile assessment was done at baseline and end of the treatment i.e., 84th day. There is considerable improvement in the lipid profile of the prediabetic subjects enrolled in the study especially significant improvement in total cholesterol level (from 266.47 ± 62.92 to 216.058 ± 40.14 with p value of 0.008**) and LDL (from 189.23 ± 55.07 to 138.58 ± 34.86 with p value of 0.003**). -Maghz-e-Jamun (Eugenia jambolana) show substantial effect on dyslipidemia in the patients of intermediate hyperglycemia.

Headache is one of the most common medical problems experienced by the majority of general population. In the latest version of the International Classification of Headache Disorders (ICHD-Ⅲ) beta in 2013, fasting headache, has been classified as a secondary headache, and a subheading of “Headache attributed to fasting”. Suggested controversial hypothesis of this medical condition include associations with hypoglycemia, sleep quality and caffeine withdrawal, although these relationships have not been confirmed yet. The principal purpose of the present study is to review the etiology and proposed preventive and treating strategies regarding fasting headache in Persian Medicine (PM) literature. This complaint is regarded as a headache associated with dryness in PM. Therefore, words related to "dryness" from PM references.  Relevant keywords were also searched in modern medical literature and PubMed, Scopus, Google scholar, Web of science and Sid databases. Obtained results were subsequently compared following classification. Fasting plays a causative role in increasing heat in the heart, liver, and stomach (and other organs), and also decreasing body moisture. Therefore, the effective management as proposed by PM is reducing the heat and increasing body moisture. More research is needed to provide academic evidence in this regard.

In Persian medicine (PM), massage is one of the principles for maintaining health.  This study presents the viewpoint of PM about massage in pediatrics and the scientific evidence for its efficacy.  The PM textbooks including Canon of Medicine, Mufarrah al-qulub, Kholase-alHekmah, Kholase-al-Tajareb, Tadbir al-hobali val atfal va-sebyan, Exir-e-Azam, Ehya-al-Atfal, Risalat-al-Dallakieh were reviewed for applications of massage in children. The keywords were Dalk, Ghamz, rubbing, and massage. The effectiveness of PM recommendations for massage in modern medicine was searched in Google Scholar, PubMed, Scopus and science direct, SID, and Magiran with the keywords massage, pediatrics, and children. The selection criteria were clinical trials or reviews on pediatric massage in English or Persian language without time limitation. Applications of pediatric massage in PM which scientific articles approve their efficacy include facilitating the growth, development, and weight gain, reducing muscle and joint pain, relieving colic and bloating, helping to treat skin dryness, and convulsion. Other applications including sore throats, colds, vomiting, and eye aberrations are needed to be evaluated in clinical studies.

Psoriasis is an inflammatory and autoimmune disease with unknown etiology. This is a chronic, recurrent, distressing and costly disease, which has a great impact on the quality of life of individuals. Its treatment varies from topical to systemic medication and sometimes with a great deal of side effects. Probably, changing nutritional habits, life style modification and applying preventive measures may reduce the high amount use of chemical drugs and the costs of the disease. This study investigates etiology, clinical manifestation and natural treatments of psoriasis from the perspective of Persian Medicine by which prevention and nutritional recommendations and some treatments can be introduced. Searching selected sources of Persian Medicine including the Canon of Medicine, Zakhirah -E- Kharazm Shahi, Kamel alsanaat, Sharh al-asbab va al-alamat, Tebbe-Akbari, Moalejate Aghili, Exir-e-Azam, three diseases named “Ghooba”, “Barase Asvad” and “Saafe-Yabes” were found to be similar to psoriasis in their manifestations. Therefore, study of their specific treatments in the levels of lifestyle management more importantly nutrition and herbal therapy could be noteworthy for the future studies.