Antihyperlipidemic Effect of Seeds of Jamun (Eugenia jambolana) in Subjects of Intermediate Hyperglycemia: A Pilot Study

Abstract

Intermediate hyperglycemia (Prediabetes) is a type of metabolic disorder with slight increase in the blood glucose levels from the normal but not reaching up to the level of diabetes. It is associated with many micro-vascular as well as macro-vascular complications. Abundance of Unani medicines are known for anti-hyperlipidemic activity, among them is Maghz-e-Jamun (Eugenia jambolana). The present study was to evaluate the anti-hyperlipidemic effect of Maghz-e-Jamun (Eugenia jambolana) in intermediate hyperglycemia. Patients diagnosed with prediabetes as per ADA criteria were randomly divided in two groups- group A was supplemented with 4.5g powder /day jamun seed powder in the form of capsules and group B was given placebo capsules. Lipid profile assessment was done at baseline and end of the treatment i.e., 84th day. There is considerable improvement in the lipid profile of the prediabetic subjects enrolled in the study especially significant improvement in total cholesterol level (from 266.47 ± 62.92 to 216.058 ± 40.14 with p value of 0.008**) and LDL (from 189.23 ± 55.07 to 138.58 ± 34.86 with p value of 0.003**). -Maghz-e-Jamun (Eugenia jambolana) show substantial effect on dyslipidemia in the patients of intermediate hyperglycemia.