Research Article

Antihyperlipidemic Effect of Seeds of Jamun (Eugenia jambolana) in Subjects of Intermediate Hyperglycemia: A Pilot Study


Intermediate hyperglycemia (Prediabetes) is a type of metabolic disorder with slight increase in the blood glucose levels from the normal but not reaching up to the level of diabetes. It is associated with many micro-vascular as well as macro-vascular complications. Abundance of Unani medicines are known for anti-hyperlipidemic activity, among them is Maghz-e-Jamun (Eugenia jambolana). The present study was to evaluate the anti-hyperlipidemic effect of Maghz-e-Jamun (Eugenia jambolana) in intermediate hyperglycemia. Patients diagnosed with prediabetes as per ADA criteria were randomly divided in two groups- group A was supplemented with 4.5g powder /day jamun seed powder in the form of capsules and group B was given placebo capsules. Lipid profile assessment was done at baseline and end of the treatment i.e., 84th day. There is considerable improvement in the lipid profile of the prediabetic subjects enrolled in the study especially significant improvement in total cholesterol level (from 266.47 ± 62.92 to 216.058 ± 40.14 with p value of 0.008**) and LDL (from 189.23 ± 55.07 to 138.58 ± 34.86 with p value of 0.003**). -Maghz-e-Jamun (Eugenia jambolana) show substantial effect on dyslipidemia in the patients of intermediate hyperglycemia.

Deepa M, et al. High burden of prediabetes and diabetes in three large cities in South Asia: The Center for Cardio-metabolic Risk REugenia jambolana eduction in South Asia (CARRS) Study. Diabetes Res Clin Pract. 2015;2:172-182.

Kansal S, Kamble TK. Lipid Profile in Prediabetes. J Assoc Phys India 2016;64:18.

Bhowmik B, et al. Serum lipid profile and its association with diabetes and prediabetes in a rural bangladeshi population. Int J Env Res Public Health 2018;2:9-11.

Anderson J, Wand K. High carbohydrates, high fibre for insulin treated man for diabetes man. Am J Clin Nutr 2008; 32: 2312-2321.

Barnard ND. A low fat vegan diet improves glycemic control and cardiovascular risk factors in randomised clinical trial in individual with type 2 diabetes mellitus. Diabetes care 2006;29: 1773-1783.

Bernard R. Fundamentals of Biostatistics. 5th edition. Duxbury. 2000; pp 80-240.

Riffenburg Robert H. Statistics in Medicine. 2nd edition. Academics Press. 2005; pp 85-125.

Rao S, Richard J. An Introduction to Biostatistics, A manual for students in health sciences. 4th edition. New Delhi. 2006; pp 86-160.

Sidana S, et al. Effect of Syzygium cumini (jamun) seed powder on glycemic control: A double-blind randomized controlled trial. J Med Soci 2017;31:185-189.

Srivastava MC. et al. A Study of Changes in Lipid Profile among Pre-diabetics and Diabetics. Int J Contem Med Research 2019;6:21-24.

Sharma SB, et al. Antihyperlipidemic effect of active principle isolated from seed of Eugenia jambolana on alloxan-induced diabetic rabbits. J Med Food 2011;14:353-359.

Kasiappan R. Rajasekaran Subbaih and Subramanian S.Antihyperlipidemic effect of Eugenia jambolana seed kernel on streptozotocin-induced diabetes in rats. Food Chem Toxicol 2005;43:1433-1439.

IssueVol 5, No 4, 2020 QRcode
SectionResearch Article(s)
Maghz-e-Jamun (Eugenia jambolana) Antihyperlipidemic Unani Prediabetes Intermediate hyperglycemia

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How to Cite
Parveen S, Khan A, Khan Q. Antihyperlipidemic Effect of Seeds of Jamun (Eugenia jambolana) in Subjects of Intermediate Hyperglycemia: A Pilot Study. Trad Integr Med. 2020;5(4):191-197.