Clinical Trial

The Effectiveness of Combination of Viola odorata L., Rosa damascena Mill. and Coriandrum sativum L. on Quality of Life of Patients with Migraine Headaches: A Randomized, Double Blinded, Placebo-Controlled Clinical Trial


Headache is one of the most common public health problems in the world, which causes patients to see a doctor. Migraine is the second most common cause of headaches after tension headaches. This study is a randomized, double blinded, placebo - controlled clinical trial, using SF36 questionnaire, to evaluate the effect of combination of Viola odorata L., Rosa damascena Mill. and Coriandrum sativum L. on the quality of life, in patients with migraine after 4 weeks. In all domains of the SF36 questionnaire, the scores after intervention in the drug group were significantly higher than the control group after 4 weeks. This study showed that, combination of V. odorata, R. damascena and C. sativum, improves the quality of life of patients with migraine.

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IssueVol 4, No 4, 2019 QRcode
SectionClinical Trial
Persian medicine; Viola; Migraine; Headache; SF36; Traditional iranian medicine; Complementary and alternative medicine (CAM); Quality of life

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How to Cite
Kamali M, Tajadini H, Seifadini R, Mehrabani M, Jahani Y, Kamali H. The Effectiveness of Combination of Viola odorata L., Rosa damascena Mill. and Coriandrum sativum L. on Quality of Life of Patients with Migraine Headaches: A Randomized, Double Blinded, Placebo-Controlled Clinical Trial. Trad Integr Med. 2019;4(4):181-190.