Traditional and Integrative Medicine 2016. 1(1):47-51.

A Traditional Iranian Medicine (Majoon-e Loboob) for Idiopathic Male Infertility: A Case Series
Soodabeh Bioos1, Esmail Nazem, Mansoor Keshavarz, MarziehBeigom Siahpoosh, Farnaz Sohrabvand, Hamid Sohanaki, Fatemeh Nejatbakhsh


Infertility is defined as the inability to conceive after 12 or more months of regular intercourse without  contraception.  Sperm abnormalities  are  introduced  as  20-47%  of  infertility  etiology. Idiopathic  male  subfertility  is  common  (40-50%).  In  the  Iranian  traditional  medicine,  many natural drugs are used for enhancing fertility. This case series was an effort to understand the role of an Iranian traditional formulation in conception. For this purpose, 13 men with infertility and idiopathic oligoasthenoteratospermia were treated by 10 g Majoon-e Loboob twice daily. 11 (84.6%) of their wives became pregnant after 4.8 ± 2.0 months. In men with severe oligoasthenospermia (< 0.1 × 106/ml), no pregnancy occurred and their spermogram remained unchanged. However, libido and erectile function showed improvement in all patients. No adverse events have been reported by patients. Majoon-e Loboob could be considered as a complementary medicine  for  treatment  of  idiopathic  infertility.  Some  of  the  natural  components  in  this formulation have proven pharmacological activity in conception including Zingiber officinale and Myristica fragrans.


Iranian Traditional Medicine; Male Infertility; Majoon-e Loboob; Sperm Parameter; Natural Remedy

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Traditional and Integrative Medicine(Quarterly)
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Tehran University of Medical Sciences, Tehran, Iran. 
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