Research Article

A Questionnaire-Based Study on Medicinal Plant Use in Patients with a Chronic Disease Diagnosis


Chronic diseases are the most common non-communicable diseases worldwide. Today, with the increase in the elderly population, the burden of the disease is gradually increasing, and alternative treatment methods for these diseases are gaining importance. Potential adverse reactions, contraindications, and interactions with prescription drugs and herbals are important to evaluate. Therefore, the use of plants by chronic patients should be under supervision of health professionals. In this study, we aimed to obtain comprehensive data by questioning the plants used by patients using drugs for chronic disease, their usage patterns, and changes seen as a result of plant use. For this purpose, 60 people over the age of 18 (47% female, 53% male) participated in the survey study, and 53.3% of the patients stated that they used plants in the treatment. Twenty-one plants have been identified. Linden and mint-lemon mixture are the most commonly used plants, accounting for 62% and 15% of the total, respectively. The most commonly used preparation method is decoction (60%). 62.5% of the users obtain the plants from herbalists' stores; 59.37% of the patients learned the use of plants through advice (friend, neighbor, relative); 96.87% of the patients stated that they benefited from the use of plants. According to these results, the patients need to be informed about the use of plants as a complementary treatment. Thus, further efforts should be made to raise awareness of the use of herbal medicine and possibility of herb-drug interactions among physicians and other health professionals.

Durna Z. Kronik Hastalıklar ve Önemi. Nobel Tıp Kitabevleri. İstanbul 2012.

World Health Organization. Noncommunicable Diseases. 2018. [online]

Saka G. Kronik hastalıklar ve halk sağlığı. Türkiye Klinikleri. Ankara 2020; pp 1-6.

Akalın E, Gürdal B, Olcay B. General overview on the conservation of medicinal plants in Turkey. Turk J Biod 2020;3:86-94.

WHO. Traditional medicine. Fifty-Sixth World Health Assembly, A56/18, 14.10, 31 March 2003.

Çakmak S, Nural N. Complementary and alternative medicine applications in chronic diseases. J Intern Med Nurs-Special Topics 2017;3:57-64.

Ernst E, Fugh-Berman A. Complementary and alternative medicine: What is it all about? Occup Environ Med 2002;59:140-144.

Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol 2014;4:177.

Şahin S. An overview of traditional, complementary and alternative medicine. Türk Aile Hek Derg 2017;21:159-162.

Özçelik G, Toprak D. Why is Phytotherapy Preferred? Ankara Med J 2015;15:48-58.

Soner BC, Sahin AS, Sahin TK. A survey of Turkish hospital patients’ use of herbal medicine. Eur J Integr Med 2013;5:547-552.

Bulut S, Karakaş N, Orhan DD. Pediatri Hastalarında Bitki ve Bitkisel İçerikli Ürün Kullanım Alışkanlıklarının Değerlendirilmesi. Sağlık ve Toplum 2021;31:172-180.

Öztürk S, Gundogdu YP, Gursu M, Yamak M, Ozkan O, et al. Use of herbal products in type 2 diabetic patients. Med Bull Haseki 2015;53:214-219.

Taşkın Şayir Ç, Aslan Karaoğlu S, Evcik Toprak D. Evaluation of polypharmacy and complementary therapy use in patients ≥65 years, attending to Family Medicine Outpatient Clinic of Şişli Etfal Training and Research Hospital. Türk Aile Hek Derg 2014;18:35-41.

Tuncay HO, Ekici M, Teke B, Akalın Uruşak E. Survey Study on Medicinal Plants and Mushrooms Use in Treatment of Cancer by Patients at The Istanbul University Institute of Oncology. J Adv Res in Health Sci 2020;3:51-60.

Yıldız Gülhan P, Üzer F, Güleç Balbay E. Evaluation of traditional and complementary medicine methods in asthmatic patients. Bozok Tıp Dergisi 2020;10:106-110.

Varlı M. Nonprescription product use among geriatric outpatients. Ankara Med J 2017;17:226-234.

Erarslan ZB, Ay S, Kültür Ş. A questionnaire-based study on medicinal plant use in respiratory diseases. J Fac Pharm Ankara 2020;44:437-451.

Renda G, Yasar YK. Primary care physicians and community pharmacists approach to the use of herbal products: a pilot study in Trabzon. Türk Aile Hek Derg 2018;22(3):141-156.

European Scientific Cooperative on Phytotherapy. E/S/C/O/P monographs: The scientific foundation for herbal medicinal products. European Scientific Cooperative on Phytotherapy. Exeter. U.K. 2003.

Yilmaz CK, Asiret GD. Identifying the constipation levels of older people and their interventions for recovery. Int J Caring Sci 2017;10:1605-1614.

Toygar İ, Yeşilbalkan Usta Ö, Kürkütlü M, Aslan A. Complementary and alternative medicines used by cancer patients to cope with chemotherapy-induced constipation. Complement Ther Clin Pract 2020;39:101-108.

Tamura M, Ohnishi Y, Kotani T, Gato N. Effects of new dietary fiber from Japanese Apricot (Prunus mume Sieb. et Zucc.) on gut function and intestinal microflora in adult mice. Int J Mol Sci 2011;12:2088-2099.

Koch E, Malek FA. Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders–preclinical and clinical studies. Planta Med 2011;77:1123-1128.

Tassell MC, Kingston R, Gilroy D, Lehane M, Furey A. Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease. Pharmacogn Rev 2010;4:32-41.

Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-915.

Asher GN. Herbal products review. What do we really know? J Am Coll Cardiol 2010;56:905-909.

Williamson E, Driver S, Baxter K (Eds.). Stockley's Herbal Medicines Interactions. Pharmaceutical Press. London 2009.

Shimoda H, Tanaka J, Kikuchi M, Fukuda T, Ito H, et al. Effect of polyphenol-rich extract from walnut on diet-induced hypertriglyceridemia in mice via enhancement of fatty acid oxidation in the liver. J Agric Food Chem 2009;57:1786-1792.

Taha NA, Al-wadaan MA. Utility and importance of walnut, Juglans regia Linn: A review. Afr J Microbiol Res 2011;5:5796-5805.

Wang L, Sun J, Li W, Lv Y, Shi W, et al. Protective effect of eucalyptus oil on pulmonary destruction and inflammation in chronic obstructive pulmonary disease (COPD) in rats. J Med Plant Res 2017;11:129-136.

Wei ZM. Effects of injection Salviae miltiorrhizae on senile chronic asthmatic bronchitis patients. Zhongguo Zhong Xi Yi Jie He Za Zhi 1996;16:402-404.

Ankolekar C, Terry T, Johnson K, Johnson D, Barbosa ACL, et al. Anti-hyperglycemia properties of Tea (Camellia sinensis) bioactives using in vitro assay models and influence of extraction time. J Med Food 2011;14:1190-1197.

Jacob B, Narendhirakannan RT. Role of medicinal plants in the management of diabetes mellitus: a review. 3 Biotech 2019;9:4.

Ahmad M, Kamran SH, Mobasher A. Protective effect of crude Curcuma longa and its methanolic extract in alloxanized rabbits. Pak J Pharm Sci 2014;27:11211128.

Wainstein J, Ganz T, Boaz M, Dayan YB, Dolev E, et al. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. J Med Food 2012;15:605-610.

IssueVol 7, No 4, 2022 QRcode
SectionResearch Article(s)
Chronic diseases Medicinal plant Complementary medicine Herbal product

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Gürdal B, Yesin E. A Questionnaire-Based Study on Medicinal Plant Use in Patients with a Chronic Disease Diagnosis. Trad Integr Med. 2022;7(4):402-408.