The Impact of Spleen Disorders in the Pathogenesis of Anemia from the Viewpoint of Persian Medicine
-
Somaye Fatali
,
Amir Hossein Emami
,
Majid Dadmehr
,
Mitra Mehrabani
,
Saeideh Yarjoo
,
Omid Sadeghpour
Abstract
Spleen is one of the main components of reticuloendothelial system and plays an important role in controlling of red blood cell quality with elimination of old and damaged cells. Physicians of Traditional Persian Medicine believed that spleen has a high incorporation with the liver, and liver has a main role in blood production. So its pathologic changes influence the production of hematologic elements in both aspects of amount and quality. In this study, chapters related to spleen disease in several Traditional Persian Medicine textbooks and available databases were reviewed. Further the relationship between anemia and spleen diseases were derived and evaluated. After interviewing two experts about the findings and reaching data saturation, the results were compiled and explained. Spleen dysfunction and diseases can lead to anemia, because of intercommunity with liver. This happens with different mechanisms such as: enlargement, cold distemperment, asthenia and crisis. Although there are many studies so far about anemia, but role of the spleen in the development of anemia is still not well known. Considering the role of the spleen in developing anemia, the drugs used in Persian medicine for spleen-originated anemia may provide an appropriate solution to treat the disease.
Cesta MF. Normal structure, function, and histology of the spleen. Toxicol Pathol 2006;34:455-465.
Wiener C, Fauci A, Braunwald E, Kasper D, Hauser S, Longo D, Jameson J, Loscalzo J, Brown C. Harrisons Principles of Internal Medicine Self-Assessment and Board Review. 18th ed. Mc Graw-Hill Education. 2012.
Nairz M, Theurl I, Wolf D, Weiss G. Iron deficiency or anemia of inflammation? : Differential diagnosis and mechanisms of anemia of inflammation. Wien Med Wochenschr 2016;166:411-423.
Barcellini W. New Insights in the Pathogenesis of Autoimmune Hemolytic Anemia. Transfus Med Hemother 2015;42:287-293.
Rhazes MZ. Al-Hawi fi al-Tibb (Liber Continent). 1st ed. Shahid Beheshti University of Medical science. Tehran 2016.
Avicenna M. Al Qanun Fi Al-Tibb. Alaalami library. beirut 2005.
shirazi M. Kefayeh Mansoori. Iran University of Medical science. Tehran 2003.
Aghili-Khorasani SMH. kholasatol-Hikmah. Choogan. Tehran 2016.
Yarjou S, Sadeghpour O, Nazem E, Emami AH. Liver function and anemia pathogenesis in Iranian traditional medicine. Iran Red Crescent Med J 2015;17:e17099.
Azam-khan M. Exir-e- Azam. Tehran university of medical science. Almaee. 2014
Ahvazi AIA. Kamil al-Sinaa al-Tibbiya. Institute of Revival of Natural Medicine. Qom 2008.
Choopani R. sawda humor from the perspective of traditional medicine, in Iranian Traditional Medicine [PhD thesis]. School of Traditional Medicine, Shahid Beheshti University of Medical Science, Iran; 2012
Yarjou S, Sadeghpour O, Nazem E, Emami AH. An overview of the main diseases (special) spleen. Journal of Islamic and Iranian Traditional medicine 2014;4:315-321.
Alizadeh M, Khadem E, Aliasl J. Diagnosis Protocol of Stomach Distemperament for Clinical Practice in Iranian Traditional Medicine: A Narrative Review. Iran J Public Health 2017;46:877-881.
Tabari A. Firdous al-Hikmah. Scientific daralkotob. Beirut 2002.
kashkari J. Connash fi al-Tibb. Iran University of Medical Science. Tehran 2007.
Kermani MK. Daqaiq al-Ilaj fi al-Tibb. Saadat. Kerman 1983.
Razi B. Kholasat al-Tajarob (Summaries of records). Iran University of Medical Science. Tehran 2003.
Jakhere S. Kumbhar R, Dhongade H. Adrenal myelolipoma, cholelithiasis and calcified spleen: retrospective diagnosis of sickle cell anemia using a novel triad of abdominal imaging findings. Acta Med Indones 2014;46:11-14.
Suvarna J, Ingle H, Deshmukh CT. Insulin resistance and beta cell function in chronically transfused patients of thalassemia major. Indian Pediatr 2006;43: 393-400.
Shi B, Zhu H, Liu YJ, Lu L, Jin CB, Ran LF, Zhou K, Yang W, Wang ZB, Mei ZC. Experimental studies and clinical experiences on treatment of secondary hypersplenism with extracorporeal high-intensity focused ultrasound. Ultrasound Med Biol 2012;38:1911-1917.
Narla J, Mohandas N. Red cell membrane disorders. Int J Lab Hematol 2017;39: 47-52.
Hoffbrand V, Moss P. Essential Haematology, Includes Desktop Edition. 6th ed. John Wiley. 2011.
Khan W, Zakai HA, Umm EA. Clinico-pathological studies of Plasmodium falciparum and Plasmodium vivax - malaria in India and Saudi Arabia. Acta Parasitol 2014;59:206-212.
Sapucahy MV, Faintuch J, Bresciani CJ, Bertevello PL, Habr-Gama A, Gama-Rodrigues JJ. Laparoscopic versus open splenectomy in the management of hematologic diseases. Rev Hosp Clin Fac Med 2003;58:243-249.
| Files | ||
| Issue | Vol 5, No 1, 2020 | |
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/tim.v5i1.2670 | |
| Keywords | ||
| Spleen; Anemia; Liver; Persian medicine | ||
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