Ethnobotanical Survey of Antidiabetic Medicinal Plants Used by Patients Visiting Health Facilities in the SALÉ Region (Morocco)
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Abstract
Herbal medicine (HM) is frequently used by diabetic patients in Morocco, although limited information exists about the specific plants used by diabetic patients in the SALÉ region. This study aims to collect a list of plant species used by diabetic patients as traditional remedies. This study is based on an ethnobotanical survey. It was carried out using questionnaires with a sample of 300 diabetic patients visiting the health centres in SALÉ. The results indicate that 93% of type 2 diabetic patients and 7% of type 1 diabetic patients use HM alongside modern medications. Patients justify their use of HM due to its easy accessibility (34.3%), greater efficacy (27.7%), and low cost (27%). The majority (60.3%) are unable to specify the dosage used, and 95.3% are unaware of the toxicity of the plants. This study identified 32 medicinal plant species from 18 botanical families, with the most commonly used plants being Olea europea L. (9.3%), Coriandrum sativum L. (7.7%), Trigonella foenum-graecum L. (7.3%), Marrubium vulgare L. (6%), Lepidium sativum L., Lawsonia inermis L., Capparis spinosa L. (5.7%), and Artemisia absinthium (5%). The most used plant parts are leaves (40%) and seeds (23.67%); with infusion and decoction being the preferred preparation methods for oral administration. The findings indicate that the SALÉ region has a wide range of HM knowledge for treating diabetes, which needs further scientific study. This knowledge can serve as a foundation for pharmacological studies to assess the antidiabetic effects of these plants.
Schleicher E, Gerdes C, Petersmann A, Müller-Wieland D, Müller UA, et al. Definition, classification and diagnosis of diabetes mellitus. Exp Clin Endocrinol Diabetes 2022;130:1-8.
Khalid M, Petroianu G, Adem A. Advanced glycation end products and diabetes mellitus: mechanisms and perspectives. Biomolecules 2022;12:542-558.
Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, et al. IDF diabetes atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract 2022;183:109119.
IDF Diabetes Atlas 10th edition 2021.
Roberts AW. Cardiovascular risk and prevention in diabetes mellitus. Clin Med 2010;10: 495-499.
Taylor SI. The high cost of diabetes drugs: disparate impact on the most vulnerable patients. Diabetes Care 2020; 43:2330-2332.
Fakchich J, Elachouri M. An overview on ethnobotanico-pharmacological studies carried out in Morocco, from 1991 to 2015: Systematic review (part 1). J Ethnopharmacol 2021;267:113200.
Elachouri M, Kharchoufa L, Fakchich J, Lorigooini Z, Subhasis P, et al. Ancestral phytotherapeutic practices in Morocco regards on history, current state, regulatory and safety of commonly used herbal medicine Arab J Chem Environ Res 2021;8:133-149.
Giannenas I, Sidiropoulou E, Bonos E, Christaki1 E, Florou-Paneri P. The history of herbs, medicinal and aromatic plants, and their extracts. In: Feed Additives. Elsevier. 2020; pp 1-18.
Benkhnigue O, Akka FB, Salhi S, Fadli M, Douira A, et al. Catalogue des plantes médicinales utilisées dans le traitement du diabète dans la région d’Al Haouz-Rhamna (Maroc). J Anim Plant Sci 2014;23:3539-3568.
Eddouks M, Maghrani M, Lemhadri A, Ouahidi ML, Jouad H. Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). J Ethnopharmacol 2002;82:97-103.
El Amrani F, Rhallab A, Alaoui T, El Badaoui K, Chakir S. Étude ethnopharmacologique de quelques plantes utilisées dans le traitement du diabète dans la région de Meknès-Tafilalet (Maroc). Phytothérapie 2010;8:161-165.
Hinad I, S’hih Y, Elhessni A, Mesfioui A, Ouahidi ML. Medicinal plants used in the traditional treatment of diabetes in Ksar Elkebir Region (North-Western Morocco). Pan Afr Med J 2022;42:319.
MNTPUPHCP. Regional monograph on the housing sector region of Rabat-Sale-Kenitra 2019.
Chase MW, Christenhusz MJM, Fay MF, Byng JW, Judd WS. An update of the Angiosperm Phylogeny Group classification for the orders and families of flowering plants: APG IV. Bot J Linn Soc 2016;181:1-20.
TPL. The WFO Plant List 2023. http://www.theplantlist.org/; https://wfoplantlist.org/plant-list.
Rehman S, Iqbal Z, Qureshi R, Mujtaba Shah G, Irfan M. Ethnomedicinal plants uses for the treatment of respiratory disorders in tribal district north waziristan, khyber pakhtunkhawa, pakistan. Ethnobot Res Appl 2023;25:1-16.
Gnagne AS, Camara D, Fofie NBY, Bene K, Zirihi GN. Étude ethnobotanique des plantes médicinales utilisées dans le traitement du diabète dans le Département de Zouénoula (Côte d’Ivoire). J Appl Biosci 2017;113:11257-11266.
El Boullani R, Barkaoui M, Lagram K, El Finti A, Kamel N, et al. The use of plants in the traditional treatment of diabetes patients: survey in southern Morocco. Not Sci Biol 2022;14:11322-11338.
Eddouks M, Ouahidi ML, Farid O, Moufid A, Khalidi A, et al. L’utilisation des plantes médicinales dans le traitement du diabète au Maroc. Phytothérapie 2007;5:194-203.
Errajraji A, Ouhdouch F, El-Anssari N. Usage des plantes médicinales dans le traitement du diabète de type 2 au Maroc. Méd Mal Métab 2010;4:301-304.
Wyatt SB, Winters KP, Dubbert PM. Overweight and obesity: prevalence, consequences, and causes of a growing public health problem. Am J Med Sci 2006;331:166-174.
Laadim M, Ouahidi ML, Zidane L, El Hessni A, Ouichou, A et al. Ethnopharmacological survey of plants used for the treatment of diabetes in the town of Sidi Slimane (Morocco). J Pharmacogn Phytother 2017;9:101-110.
Alami Z, Aynaou H, Alami B, Hdidou Y, Latrech H. Herbal medicines use among diabetic patients in Oriental Morocco. J Pharmacogn Phytother 2015;7:9-17.
Mechchate H, Es-safi I, Jawhari FZ, Bari A, Grafov A, et al. Ethnobotanical survey about the management of diabetes with medicinal plants used by diabetic patients in Region of Fez-Meknes, Morocco. Ethnobot Res Appl 2020;19:1-28.
El Amrani F, Rhallab A, Alaoui T, El Badaoui K, Chakir S. Étude ethnopharmacologique de quelques plantes utilisées dans le traitement du diabète dans la région de Meknès-Tafilalet (Maroc). Phytothérapie 2010;8:161-165.
Kendall DM, Cuddihy RM, Bergenstal RM. Clinical application of incretin-based therapy: therapeutic potential, patient selection and clinical use. Am J Med 2009;122:37-50.
Chetoui A, Kaoutar K, Boutahar K, El Kardoudi A, BenChaoucha-Chekir R, et al. Herbal medicine use among Moroccan type 2 diabetes patients in the Beni Mellal-Khenifra region. J Herb Med 2021;29:1-9.
Seeff LB, Bonkovsky HL, Navarro VJ, Wang G. Herbal products and the liver: a review of adverse effects and mechanisms. Gastroenterology 2015;148:517-532.
Hachi M, Benkhnigue O, Hachi T, El Bouhaddioui M, Bouabadi I, et al. Contribution to the ethnobotanical study of antidiabetic medicinal plants of the Central Middle Atlas region (Morocco). Lazaroa 2016;37:135-144.
Hassaïne S, Benmalek S. Medicinal plants traditionally used in the Algerian Sahara: an ethnobotanical study. Vegetos 2022;36:400-426.
Naceiri Mrabti H, Bouyahya A, Naceiri Mrabti N, Jaradat N, Doudach L, et al. Ethnobotanical survey of medicinal plants used by traditional healers to treat diabetes in the taza region of Morocco. Evid Based Complement Alternat Med 2021;2021:5515634..
Tarak D, Namsa ND, Tangjang S, Arya SC, Rajbonshi B, et al. An inventory of the ethnobotanicals used as anti-diabetic by a rural community of Dhemaji district of Assam, Northeast India. J Ethnopharmacol 2011;138:345-350.
Wasana KGP, Attanayake AP, Arawwawala LDAM. Ethnobotanical survey on medicinal plants used for the treatment of diabetes mellitus by Ayurveda and traditional medicine practitioners in Galle district of Sri Lanka. Eur J Integr Med 2022;55:102177.
Kumar S, Saini R, Suthar P, Kumar V, Sharma R. Plant secondary metabolites: Their food and therapeutic importance. In: Plant Secondary Metabolites: Physico-Chemical Properties and Therapeutic Applications. Springer. 2022; pp 371-413.
Brahmi F, Iblhoulen Y, Issaadi H, Fahmi Elsebai M, Madani, K et al. Ethnobotanical survey of medicinal plants of bejaia localities from algeria to prevent and treat coronavirus (COVID-19) infection shortened title: phytomedicine to manage COVID-19 pandemic. Adv Tradit Med 2022.
El Finou H, Salhi N, Halmoune A, El Rhaffari L. Ethnobotanical survey of aromatic and medicinal plants used in traditional medicine and agri-food in the fez-meknes region. Nat Prod Chem 2023;12:133-141.
Kadir MF, Bin Sayeed MS, Shams T, Mia MMK. Ethnobotanical survey of medicinal plants used by Bangladeshi traditional health practitioners in the management of diabetes mellitus. J Ethnopharmacol 2012;144:605-611.
| Issue | Vol 10, No 2, 2025 (In Press) | |
| Section | Research Article(s) | |
| Keywords | ||
| Ethnobotanical survey Herbal medicine Diabetes mellitus the SALÉ region Morocco | ||
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