Research Article

The Frequency of Medicinal Plant Usage during Pregnancy and possible Related Factors; A Cross-Sectional Study from Tehran, Iran

Abstract

Taking medicinal plants during pregnancy may be associated with geographical, socioeconomic, cultural, and individual factors. The present study was conducted to evaluate the frequency of medicinal plant usage and its influencing factors among pregnant mothers living in Tehran, Iran. A cross-sectional study was conducted (Tehran, Iran; 2019-2020). All pregnant women who attended the prenatal clinic were invited. A written consent was obtained from all subjects before enrolment. Data regarding medicinal plant consumption, the reasons for usage, the cause of preference, the source of advice, and the preparation route were gathered through an interview and the completion of a questionnaire. The recorded data were analyzed to assess the prevalence, indications, and factors influencing medicinal plant usage during pregnancy. Of 326 pregnant women, 105 (32.2%) used at least one, and 221 (67.8%) used no medicinal plant. The most consumed medicinal plant was ginger, followed by peppermint, thyme, frankincense, chicory, and saffron. The main reasons for usage were digestive disease and cold symptoms. The place of receiving prenatal care was the only significant factor affecting herbal medicine consumption (p=0.01). More analyses showed a relatively significant correlation between the participant’s age and medicinal plants usage (p=0.05). The results also showed that belief in low adverse effects and high effectiveness of medicinal plants were the reasons for preference of herbal medicine usage. Furthermore, 37 subjects (35.0%) informed by their family or friends, and 15 (14.3%) consumed medicinal plants on their data. Plants were mainly provided by herbal stores. The results showed a relatively frequent use of medicinal plants. The plants were mostly recommended by families and friends. Future studies with larger sample sizes are suggested to determine possible teratogenicity and safe doses.

Widoyo H, Mohammed ZY, Ramírez-Coronel AA, Iswanto AH, Thattarauthodiyil U, et al. Herbal therapy in Covid-19: A systematic review of medicinal plants effective against Covid-19. Casp J Environ Sci 2023;21:1289-1298.

Marrelli M. Medicinal plants. Plants (Basel, Switzerland). 2021;10:1355.

John LJ, Shantakumari N. Herbal medicines use during pregnancy: a review from the Middle East. Oman Med J 2015;30:229-236.

Ahmed SM, Nordeng H, Sundby J, Aragaw YA, de Boer HJ. The use of medicinal plants by pregnant women in Africa: a systematic review. J Ethnopharmacol 2018;224:297-313.

Mekuria AB, Erku DA, Gebresillassie BM, Birru EM, Tizazu B, et al. Prevalence and associated factors of herbal medicine use among pregnant women on antenatal care follow-up at University of Gondar referral and teaching hospital, Ethiopia: a cross-sectional study. BMC complement Altern Med 2017;17:1-7.

Allaire AD. Complementary and alternative medicine in the labor and delivery suite. Clin Obstet Gynecol 2001;44:681-691.

Jasim SA, Abdelbasset WK, Jawad MA, Bokov DO, Thangavelu L, et al. Tramadol toxicity phytotherapy: The protective role of medicinal plants against tramadol toxicity. Casp J Environ Sci 2023;21:227-243.

Baharvand Ahmadi B, Khajoei Nejad F, Papi S, Eftekhari Z. Phytotherapy for heart tonic: An ethnobotanical study in Dehloran city, Ilam province, western Iran. Casp J Environ Sci In Press.

Kam PC, Barnett DW, Douglas ID. Herbal medicines and pregnancy: A narrative review and anaesthetic considerations. Anaesth Intensive Care 2019;47:226-234.

Zargoush-Nasab A, Karimi E, Jalilian A, Bahmani M. Quantitative analysis of ethanol and methanol in herbal distillates distributed in ilam city in western iran using gas chromatography. Plant Biotechnol Persa 2023;5:33-38.

Azaizeh H, Saad B, Cooper E, Said O. Traditional Arabic and Islamic medicine, a re-emerging health aid. Evid Based Complement Altern Med 2010;7:419-424.

Heydarpour F, Heydarpour S, Dehghan F, Mohammadi M, Farzaei MH. Prevalence of medicinal herbs use during pregnancy in the world: a systematic review and meta-analysis. J Chem Health Risks 2022;12:183-196.

Bernstein N, Akram M, Yaniv‐Bachrach Z, Daniyal M. Is it safe to consume traditional medicinal plants during pregnancy? Phytother Res 2021;35:1908-1924.

Organization WH. WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residues: World Health Organization 2007.

Mensah M, Komlaga G, Forkuo AD, Firempong C, Anning AK, et al. Toxicity and safety implications of herbal medicines used in Africa. Herb Med 2019;63:1992.

Adams J. Growing popularity of complementary and alternative medicine during pregnancy and implications for healthcare providers. Expert Rev Obstet Gynecol 2011;6:365-366.

Khadivzadeh T, Ghabel M. Complementary and alternative medicine use in pregnancy in Mashhad, Iran, 2007-8. Iran J Nurs Midwifery Res 2012;17:263.

Sattari M, Dilmaghanizadeh M, Hamishehkar H, Mashayekhi SO. Self-reported use and attitudes regarding herbal medicine safety during pregnancy in Iran. Jundishapur J Nat Pharm Prod 2012;7:45-49.

Yazdi N, Salehi A, Vojoud M, Sharifi MH, Hoseinkhani A. Use of complementary and alternative medicine in pregnant women: A cross-sectional survey in the south of Iran. J Integr Med 2019;17:392-395.

Vardanjani HM, Steel A, Mofarrahi D, Jaladat AM, Amini F, et al. Use of complementary and alternative medicine and its related factors among pregnant women in Shiraz, South of Iran: A cross-sectional study. Iran J Nurs Midwifery Res 2023;28:53-59.

Abdollahi F, Yazdani Chareti J. The relationship between women’s characteristics and herbal medicines use during pregnancy. Women & Health. 2019;59(6):579-90.

Ekrasarian S, Rostami F, Yazdani Charati J, Abdollahi F. Use of Medicinal Plants during Pregnancy in Pregnant Women in Sari, Iran. J Mazandaran Uni Med Sci 2017;26:341-345.

Hashem Dabaghian F, Abdollahi Fard M, Shojaei A, Kianbakht S, Zafarghandi N, et al. Use and attitude on herbal medicine in a group of pregnant women in Tehran. 2012;11:22-33.

Illamola SM, Amaeze OU, Krepkova LV, Birnbaum AK, Karanam A, et al. Use of herbal medicine by pregnant women: What physicians need to know. Front Pharmacol 2020;10:1483.

Alema NM, Semagn G, Melesse S, Araya EM, Gebremedhin H, et al. Patterns and determinants of prescribed drug use among pregnant women in Adigrat general hospital, northern Ethiopia: a cross-sectional study. BMC Pregnancy Childbirth 2020;20:624.

Bouqoufi A, Lahlou L, Ait El Hadj F, Abdessadek M, Obtel M, et al. Prevalence, motivation, and associated factors of medicinal herbs consumption in pregnant women from Eastern Mediterranean Regional Office: a systematic review. Pharm Biol 2023;61:1065-1081.

El Hajj M, Sitali DC, Vwalika B, Holst L. Herbal medicine use among pregnant women attending antenatal clinics in Lusaka Province, Zambia: A cross-sectional, multicentre study. Complement Ther Clin Pract 2020;40:101218.

Kennedy D, Lupattelli A, Koren G, Nordeng H. Safety classification of herbal medicines used in pregnancy in a multinational study. BMC complement Altern Med 2016;16:102.

Ahmed M, Hwang JH, Choi S, Han D. Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review. BMC complement Altern Med 2017;17:489.

Karagözoğlu Y, KIRAN TR. Investigation of heavy metal contents in thyme (thymus vulgaris) and ginger (zingiber officinale) sold in bingöl herbalists. Mid Black Sea J Health Sci 2023;9(1):88-97.

Tabatabaee M. Use of herbal medicine among pregnant women referring to Valiasr Hospital in Kazeroon, Fars, South of Iran. J Med Plants 2011;10:96-108.

Ajam M, Reyhani T, Roshanravan V, Zare Z. Increased miscarriage rate in female farmers working in saffron fields: a possible effect of saffron toxicity. Asia Pac J Med Toxicol 2014;3:73-75.

Bostan HB, Mehri S, Hosseinzadeh H. Toxicology effects of saffron and its constituents: a review. Iran J Basic Med Sci 2017;20:110-121.

Mollart L, Skinner V, Adams J, Foureur M. Midwives’ personal use of complementary and alternative medicine (CAM) influences their recommendations to women experiencing a post-date pregnancy. Women Birth 2018;31:44-51.

Mollart L, Stulz V, Foureur M. Midwives knowledge and education/training in complementary and alternative medicine (CAM): A national survey. Complementary therapies in clinical practice. 2021;45:101473.

Adane F, Seyoum G, Alamneh YM, Abie W, Desta M, et al. Herbal medicine use and predictors among pregnant women attending antenatal care in Ethiopia: a systematic review and meta-analysis. BMC Pregnancy Childbirth 2020;20:157.

Elba F, Hilmanto D, Poddar S. Factors influencing the use of herbal medications during pregnancy at Public Health Center, Indonesia. J Public Health Res 2022;11.

El Hajj M, Holst L. Herbal medicine use during pregnancy: a review of the literature with a special focus on sub-Saharan Africa. Front Pharmacol 2020;11:866.

Moreira DdL, Teixeira SS, Monteiro MHD, De-Oliveira ACA, Paumgartten FJ. Traditional use and safety of herbal medicines. Revista Brasileira de Farmacognosia 2014;24:248-257.

de Sousa Lima CM, Fujishima MAT, de Paula Lima B, Mastroianni PC, de Sousa FFO, et al. Microbial contamination in herbal medicines: a serious health hazard to elderly consumers. BMC Complement Med Ther 2020;20:17.

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IssueVol 9, No 3, 2024 QRcode
SectionResearch Article(s)
DOI https://doi.org/10.18502/tim.v9i3.16528
Keywords
Plants Medicinal Pregnancy Frequency

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How to Cite
1.
Shabani A, Nikbakht Fini H, Farahani Z, Yaghmaei M. The Frequency of Medicinal Plant Usage during Pregnancy and possible Related Factors; A Cross-Sectional Study from Tehran, Iran. Trad Integr Med. 2024;9(3):246-253.