Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 87 89 EN Bahram Mehrtash Department of Internal Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Marzieh-Beygom Siahpoosh Iranian Traditional Medicine Association, Tehran AND Clinic of Traditional Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Fatemeh Nejatbakhsh Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran 2016 10 04 2016 10 04 No Abstract https://jtim.tums.ac.ir/index.php/jtim/article/view/47 https://jtim.tums.ac.ir/index.php/jtim/article/download/47/61

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 90 95 EN Mojgan Tansaz Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mansoor Keshavarz Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Rasool Choopani Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Roshanak Mokaberinejad Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Soodabeh Bioos Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Fattaneh Hashem-Dabaghian Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran Majid Emtiazy Department of Iranian Traditional Medicine, School of Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Ardakan, Iran Farnaz Sohrabvand Department of Infertility, Vali-e-Asr Hospital, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2016 10 02 2016 10 02 This study was designed to compare the findings of hysterosalpingography and “garlic test” toassess the fallopian tubes and uterus for diagnosis of obstruction in internal female genital tract.This survey was done using the database from 50 infertile women assessed for infertility both via hysterosalpingography and garlic test. The concordance between the two tests was evaluated using overall agreement percent and kappa coefficient. The sensitivity and specificity for garlic test were 56% and 75%, respectively, with 60% positive and 72% negative predictive values. The concordance between the two assays was 67.5% with a corresponding coefficient of31%. Thus, it seems that garlic test is an easy, noninvasive and safe method. Specificity and negative predictive value of garlic test is relatively suitable but its diagnostic sensitivity and positive predictive value is not high. It can be repeated during infertility treatment for several times and seems to have favorable compliance by the patient compared to hysterosalpingography https://jtim.tums.ac.ir/index.php/jtim/article/view/40 https://jtim.tums.ac.ir/index.php/jtim/article/download/40/54

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 96 100 EN Seyede Nargess Sadati Lamardi Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Somayeh Jahantab Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran Parisa Ziyarati Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran Mahnaz Khanavi Department of Pharmacognosy and Persian Medicine AND Pharmacy Research Center, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Mohammad Reza Shams-Ardekani Department of Pharmacognosy and Persian Medicine AND Pharmacy Research Center, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 2016 10 02 The genus Ajuga is used for the treatment of joint pain, gout, jaundice, and wound healing in Iranian traditional medicine. Ajuga chamaecistus ssp. tomentella is an exclusive subspecies of Ajuga chamaecistus in the flora of Iran. Plants belong to Ajuga species are advantageous sources of phytoecdysteroids. 20-hydroxyecdysone (20E) is an important phytoecdysteroid with anabolic property. This study aimed to determine and quantify 20E in methanolic extract of aerial parts of Ajuga chamaecistus ssp. tomentella. The standard reference of 20E was isolated from n-butanolic fraction of aerial parts of Ajuga chamaecistus ssp. tomentella using high-performance liquid chromatography (HPLC). The analysis was carried out on an ODSA (C18) column with isocratic elution using water–acetonitrile (75:25). The standard calibration curve represented good linearity (r2 = 0.9997). The limit of quantification (S/N = 10) and detection (S/N = 3) were determined as 7.93  and  2.38  µg/ml,  respectively.  The  content  of  20E  in  methanolic  extract  of  Ajuga chamaecistus ssp. tomentella was determined to be 2.58% (w/w) (0.46% in dry plant). The quantitative proportion of the 20E found in Ajuga chamaecistus ssp. tomentella extract proposes the possible uses of this plant in commercial formulations or as a source of 20E. https://jtim.tums.ac.ir/index.php/jtim/article/view/41 https://jtim.tums.ac.ir/index.php/jtim/article/download/41/55

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 101 107 EN Seyede Zahra Emami-Razavi Department of Physical Medicine and Rehabilitation, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Majid Khamessi Department of Physical Medicine and Rehabilitation, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran Bijan Forough Department of Physical Medicine and Rehabilitation, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran Mehrdad Karimi Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Korosh Mansoori Department of Physical Medicine and Rehabilitation, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran Simin Sajadi Department of Physical Medicine and Rehabilitation, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran Mohadeseh Azadvari Department of Physical Medicine and Rehabilitation, Imam Khomeini Hospital, Tehran University of MedicalSciences, Tehran, Iran 2016 10 02 2016 10 02 Knee osteoarthritis is considered as a major public health issue causing chronic disability worldwide with the increasing number of aging people. Many sufferers with knee osteoarthritis are using complementary and alternative medicine including herbal drug, herbal patch, etc. This research aimed to compare the efficacy of galbanum oil in the management of knee osteoarthritis with diclofenac gel using parallel randomized controlled design. In this randomized controlled trial (RCT), 32 patients with chronic knee pain due to osteoarthritis were randomly allocated into two equal groups. The intervention group received topical galbanum oil and control group received topical diclofenac gel. The drugs were given for 1 month, 3 times per day. Outcomes were assessed using Persian version of Western Ontario McMaster University Osteoarthritis Index (WOMAC) and visual analog scale (VAS). No statistically significant difference was observed between the topical galbanum oil and topical diclofenac gel regarding knee pain, morning stiffness and physical function over the 1- and 2-months follow-up period. It seems that using topical galbanum oil is clinically effective for patients suffering from knee osteoarthritis in order to decrease their pain, morning stiffness and limited function; its effect is comparable with topical diclofenac gel. Considering lesser side effects of galbanum and its herbal base, it may be a better choice compared to topical diclofenac in management of the pain of knee osteoarthritis at least in short term. https://jtim.tums.ac.ir/index.php/jtim/article/view/42 https://jtim.tums.ac.ir/index.php/jtim/article/download/42/56

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 108 114 EN Arman Zargaran Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran AND Pharmaceutical Sciences Research Center, Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Pouya Faridi Pharmaceutical Sciences Research Center, Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy AND Research Office for the History of Persian Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Saeid Daneshamouz Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Afshin Borhani-Haghighi Clinical Neurology Research Center AND Department of Neurology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Amir Azadi Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad-Hashem Hashempur Department of Traditional Medicine, Fasa University of Medical Sciences, Fasa, Iran Abdolali Mohagheghzadeh Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran 2016 10 02 2016 10 02 Medicinal oils were of the pharmaceutical dosage forms used since ancient Persian times to now in Iran. Chamomile  oil is one of the medicinal  oils prepared by the extraction of the chamomile flowers to sesame oil as an oily vehicle. It was widely used in the history of Persian medicine and is currently used by traditional practitioners of Persian Medicine in various disorders mainly in topical form. In this study, traditional chamomile oil was prepared based on the Qarabadin books. In advanced, 600 g of chamomile flower powder was boiled in 3.6 liter of water for 3 hours. Then, powder was removed and remained water (aqueous extract of chamomile) was boiled with 0.5 liter of sesame oil for 2 hours (until all the water was vaporized and oil remained). For standardization, the essential oil of chamomile oil was obtained via Clevenger apparatus method and then analyzed with the help of gas chromatography (GC)-mass method. In addition, total phenolic and flavonoid contents of the chamomile oil were calculated based on galic acid and quercetin, respectively. The results show that the main component of the essential oil were Caryophyllene (7.45%), Bisabolol Oxide  B (2.05%),  Bisabolone  Oxide  A (62.35%),  Chamazulene  (2.05%),  Bisabolol  Oxide  A (15.54%)  and Methyl ester 5,8,11-Heptadecatriynoic acid (5.52%). Besides, total phenolic and flavonoid contents were 11.0043 ± 0.4514 and 2.7640 ± 0.1776 mg/l, respectively.  Our results show that the historical dosage form of chamomile oil in Persian medicine can be reproduced and is an stable and homogeneous oil and be standardized in our investigation https://jtim.tums.ac.ir/index.php/jtim/article/view/43 https://jtim.tums.ac.ir/index.php/jtim/article/download/43/57

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 115 121 EN Mohammad-Khalil Kargar-Shoragi Department of Sport Physiology, School of Physical Education, University of Sistan and Baluchestan, Zahedan, Iran Mohsen Ghofrani Department of Sport Physiology, School of Physical Education, University of Sistan and Baluchestan, Zahedan, Iran Laleh Bagheri Department of Physical Education, School of Literature and Humanities, Shahrekord University, Shahrekord, Iran Saeid Emamdoost Tehran University of Medical Sciences, Tehran, Iran Khadijeh Otadi Department of Physical Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran 2016 10 02 2016 10 02 Physical exercise acts as a mechanical stressor that can provoke biochemical alterations. Accordingly, muscular effort is able to modify blood concentrations in some cellular enzymes. Cupping is one of the traditional methods used to restore and revive the balance of the budy. This study aimed to evaluate the impact of cupping and a practice session on the level of some liver enzymes in men handball team members of Zahedan city, Iran. The participants were all the members of the Zahedan men handball team with the mean age of 23.66 ± 5.86 years, mean height of 177.19 ± 4.58 cm, mean weight of 80.12 ± 12.58 kg and mean body mass index (BMI) of 24.53 ± 3.60 kg/m2. All the team members, as the samples, were chosen via voluntary  sampling  method on a voluntary  basis. They were randomly  positioned  into two groups of training (n = 12) and cupping (n = 10). Serum concentrations  of creatine kinase (CK) and lactate dehydrogenase (LDH) were measured before and immediately and 24 hours after  the  training  and  cupping  using  the  enzyme-linked   immunosorbent   assay  (ELISA) methods.  Data  were  analyzed  using  independent-t  test  and  multi  variety.  There  was  a significant difference between the average concentration of the enzymes in before, next, and 24 hours after the test. According to the results of this study, the exercise and cupping caused muscle damage and increased the damage markers in blood https://jtim.tums.ac.ir/index.php/jtim/article/view/44 https://jtim.tums.ac.ir/index.php/jtim/article/download/44/58

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 122 128 EN Fatemeh Aliasl Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Tayebeh Toliyat Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Ali Mohammadi Department of Drug and Food Control, School of Pharmacy AND Medical Nanotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran Bagher Minaee Department of Traditional Medicine, School of Persian Medicine AND Department of Histology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Nasrin Samadi Department of Drug and Food Control, Pharmaceutical Sciences Research Center AND Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran Jale Aliasl Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran Omid Sadeghpour Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran 2016 10 02 2016 10 02 Cydonia oblonga Mill is commonly  known as quince. It seems to have been used since the ancient  time.  Quince  is a popular  fruit  because  of its health  promoting  properties.  It is an undeniable  fact that there is a positive relationship  between a diet rich in plant foods and a diminish  incidence  of cancer,  cardiovascular  and other diseases.  The aim of this study  was demonstrating  pharmacologic  properties of quince (pulp and peel), view of Iranian traditional medicine (ITM) and modern phytotherapy. For this purpose, Pubmed, Elseveir, Scopus, SID and Google scholar were searched for the key terms “Cydonia oblonga” and “Quince” up to 20st June 2015, and also Iranian traditional medicine manuscripts and herbal medicine books were studied. All experimental and animal studies that included the evidences of fruit (pulp and peel) written in this article were selected for review. Quince has various pharmacological  properties including antioxidant,  anti-allergic,  anti-inflammatory,  anticancer,  antibacterial,  and anticolitis properties and effects on blood pressure and blood rheology, and also has several traditional medicine uses. In Iranian traditional medicine, quince pulp is effective on the most important and vital organs like brain, heart and liver. This fruit is a valuable source of compounds with health-promoting properties and can be used as good sources of antioxidants in our diet and may have use in the prevention and treatment of heart, brain and gastrointestinal diseases https://jtim.tums.ac.ir/index.php/jtim/article/view/45 https://jtim.tums.ac.ir/index.php/jtim/article/download/45/59

Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 129 131 EN Nastaran Ebadi Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Fatemeh Farjadmand Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Mozhgan Mehri Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Fahimeh Mohajerani Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Azadeh Raies-Dana Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Zahra Shahpiri Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Roja Rahimi Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran 2016 10 02 2016 10 02 Adiantum Capillus veneris L. from the family Polypodiaceae, is one of the medicinal herbs used in  Iranian traditional  medicine (ITM).  It has been identified as “Parsiavashan”  in  Iranian traditional medicine and commonly known as “Maidenhair fern” in English. Triterpenoids and flavonoids are the major compounds identified in Maidenhair fern. It has been used in Iranian traditional medicine for treating respiratory tract diseases, irregular menstruation, flatulence, jaundice, splenomegaly and scrofula. It has been topically used in skin and hair disorders, too. The pharmacological activities reported from this plant are anti-inflammatory, antinociceptive, antimicrobial, antidiabetic, diuretic and antioxidant. However, there is not direct relationship between pharmacological activities of this plant in Iranian traditional medicine and modern phytotherapy; the anti-inflammatory and antimicrobial properties of this plant could make it useful for respiratory tract disorders. Anyway, it is recommended to design experimental and clinical studies on pharmacological activities and indications of Adiantum capillus veneris mentioned in Iranian traditional medicine literatures https://jtim.tums.ac.ir/index.php/jtim/article/view/46 https://jtim.tums.ac.ir/index.php/jtim/article/download/46/60