Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 3 2016 10 04 122 128 EN Fatemeh Aliasl Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Tayebeh Toliyat Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Ali Mohammadi Department of Drug and Food Control, School of Pharmacy AND Medical Nanotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran Bagher Minaee Department of Traditional Medicine, School of Persian Medicine AND Department of Histology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Nasrin Samadi Department of Drug and Food Control, Pharmaceutical Sciences Research Center AND Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran Jale Aliasl Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran Omid Sadeghpour Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran 2016 10 02 2016 10 02 Cydonia oblonga Mill is commonly  known as quince. It seems to have been used since the ancient  time.  Quince  is a popular  fruit  because  of its health  promoting  properties.  It is an undeniable  fact that there is a positive relationship  between a diet rich in plant foods and a diminish  incidence  of cancer,  cardiovascular  and other diseases.  The aim of this study  was demonstrating  pharmacologic  properties of quince (pulp and peel), view of Iranian traditional medicine (ITM) and modern phytotherapy. For this purpose, Pubmed, Elseveir, Scopus, SID and Google scholar were searched for the key terms “Cydonia oblonga” and “Quince” up to 20st June 2015, and also Iranian traditional medicine manuscripts and herbal medicine books were studied. All experimental and animal studies that included the evidences of fruit (pulp and peel) written in this article were selected for review. Quince has various pharmacological  properties including antioxidant,  anti-allergic,  anti-inflammatory,  anticancer,  antibacterial,  and anticolitis properties and effects on blood pressure and blood rheology, and also has several traditional medicine uses. In Iranian traditional medicine, quince pulp is effective on the most important and vital organs like brain, heart and liver. This fruit is a valuable source of compounds with health-promoting properties and can be used as good sources of antioxidants in our diet and may have use in the prevention and treatment of heart, brain and gastrointestinal diseases https://jtim.tums.ac.ir/index.php/jtim/article/view/45 https://jtim.tums.ac.ir/index.php/jtim/article/download/45/59