Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 1 2 2016 03 16 82 86 EN Maryam Ranjbar Department of Iranian Traditional Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Fatemeh Aliasl Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Fatemeh Nejatbakhsh Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran Laila Shirbegi Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran 2016 03 16 Vitiligo as a common depigmenting skin disorder plays a very important role in patient’s quality of life. It can cause serious emotional stress, which necessitates its treatment. Because of lack of desirable efficacy of conventional therapies, considering complementary therapies for the management of vitiligo is increasing. The aim of this article is to describe Iranian traditional medicine  (ITM)  approach  to  vitiligo  mechanism  and  prognosis  as  well  as  medicinal  plants proposed for the management of this disease. ITM believes human body organs consist of four fundamental humors. All of them are composed of very specific quantity and quality and any kind of diseases supposedly, is the result of excess or deficit of these humors. Changes in the quantity of “phlegm humor” and improper function of “expulsive faculty” are two main causes of vitiligo. In  this  paper,  the  vitiligo  prognosis  according  to  ITM  and  recommended  herbal  medicines according to the stage of disease have been explained. https://jtim.tums.ac.ir/index.php/jtim/article/view/29 https://jtim.tums.ac.ir/index.php/jtim/article/download/29/37