Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 11 3 2026 10 01 2330 2330 Ayoub Amssayef Laboratory of Biotechnology, Conservation and Valorization of Bioresources (BCVB), Department of Biology, Faculty of Sciences Dhar Mehraz, Sidi Mohamed Ben Abdellah University, 30000 Fez, Morocco Hasna Chaab El Asri Laboratory of Biotechnology, Conservation and Valorization of Bioresources (BCVB), Department of Biology, Faculty of Sciences Dhar Mehraz, Sidi Mohamed Ben Abdellah University, 30000 Fez, Morocco Mohammed Ajebli Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, Errachidia, Morocco. BP 509, Boutalamine, Errachidia, Morocco Hamza Elbouny Biochemistry of Natural Ressources Team, Faculty of Sciences and Techniques, Errachidia, Moulay Ismail Universty, Meknes, Morocco AND Higher School of Technology Fkih Ben Salah, Sultan Moulay Slimane University, Fkih Ben Salah, Morocco Lina Amrani Institue of biological sciences, Universiti Malaya, Kuala Lumpur, 59200, Malaysia Mohammed Benyahya Laboratory of Biotechnology, Conservation and Valorization of Bioresources (BCVB), Department of Biology, Faculty of Sciences Dhar Mehraz, Sidi Mohamed Ben Abdellah University, 30000 Fez, Morocco Raja Guemmouh Laboratory of Biotechnology, Conservation and Valorization of Bioresources (BCVB), Department of Biology, Faculty of Sciences Dhar Mehraz, Sidi Mohamed Ben Abdellah University, 30000 Fez, Morocco Damaris Silveira Pharmacy Department, Health Sciences School, University of Brasília, Brasilia 70910-900, Brazil 2025 08 23 2026 04 25 Morocco has been experiencing a widespread measles outbreak, and medicinal herbs may represent an  important therapeutic resource for manypopulations. This work aims to explore the ethnopharmacological uses of medicinal plants for measles treatment in Fez region in Morocco. Ethnobotanical data were collected through  structured questionnaire administratedvia direct interviews with herbalists. Ethnobotanical indices applied included the relative frequency of citation (RFC), use value (UV), and family use value (FUV). A total of 100 herbalists in the city of Fez agreed to participate (94 men and 6 women), aged between 20 and 80 years, with  educational levels predominantly at the of primary and secondary stages. The herbalists reported 39 plants, distributed across 36 genera and 22 families, as treatments for measles. The most represented family was Lamiaceae (7 species, 18%), while  Ranunculaceae recorded the highest FUV (0.12). The most cited species was Nigella sativa (RFC = UV = 0.12), followed by Zingiber officinale (RFC = UV = 0.11), and Salvia rosmarinus, Citrus limon, and Saussurea costus with RFC equal to 0.06. Seeds were the most used parts (39%), while powder (38%) and infusion (27%) were the dominant preparation modes. Additionally, herbalists recommended the use of other natural substances, including goat hair, beehive products, and sulfur. This study highlights the existence of indigenous ethnomedicinal knowledge of medicinal plants used to treat measles in the Fez region, andthe documented plants may serve as a foundation for future scientific research. https://jtim.tums.ac.ir/index.php/jtim/article/view/2330