Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 4 1 2019 03 18 22 27 Yessenia García Gómez Faculty of Medicine, Autonomous University of the State of Mexico (UAEMex). Paseo Tollocan s/n Esq. Jesús Carranza. Col. Moderna de la Cruz. C.P. 50180. Toluca, Mexico Martha Ruth Mendieta Alcántara Diabetes Clinic, Regional Hospital “Gral. Ignacio Zaragoza”, ISSSTE. General Ignacio Zaragoza 1711, Ejército Constitucionalista, Iztapalapa, 09220, Ciudad de México Hugo Mendieta Zerón Faculty of Medicine, Autonomous University of the State of Mexico (UAEMex). Paseo Tollocan s/n Esq. Jesús Carranza. Col. Moderna de la Cruz. C.P. 50180. Toluca, Mexico AND Asociación Científica Latina A.C. (ASCILA) and Ciprés Grupo Médico S.C. (CGM), Felipe Villanueva sur 1209 Col. Rancho Dolores CP. 50170, Toluca, Mexico 2018 09 24 2018 11 13 Herbal medicine represents an alternative for treating dyslipidemia. It has been probed that aerial part of Eryngium heterophyllum, a species of medicinal plant that belongs to the family Apiaceae, reduces cholesterol by 27% in rats. On the other hand, Amphipterygium adstringens, a Mexican tree exerts a significant hypocholesterolemic effect on rats, lowering cholesterol levels by 31%. The aim of this project was to evaluate the PC-300 tea (Eryngium heterophyllum egelm + Amphipterygium adstringens) against hypertriglyceridemia. It was a non-randomized, descriptive, prospective, longitudinal, and comparative clinical study. Voluntary subjects were assigned sequentially into two treatment groups: 1) fibrate (bezafibrate) 200 mg/day, and 2) PC-300 tea, one cup half an hour before eating. Baseline samples of serum total cholesterol and triglycerides were obtained and measured again after 1 month of treatment. There were 17 patients (males: 6, females: 11) treated with the tea, with a mean age of 49 ± 15 years, and 17 patients (males: 8, females: 9) treated with bezafibrate, with a mean age of 44.7 ± 13 years. In the first group, the percentage of triglyceride reduction was 19.7% (p ≤ 0.05), while in the second group, this was 44.8% (p ≤ 0.001). We conclude that consumption of PC-300 reduces triglyceride levels an average of 20% after 1 month. https://jtim.tums.ac.ir/index.php/jtim/article/view/166