Tehran University of Medical Sciences Traditional and Integrative Medicine 2476-5104 9 1 2024 03 06 66 73 Mahdie Hajimonfarednejad Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Babak Daneshfard Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran AND Persian Medicine Network (PMN), Universal Scientific Education and Research Network (USERN), Tehran, Iran Mohammad Javad Raee Centre for Nanotechnology in Drug Delivery, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Dennis Cordato Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW, Australia AND Department of Neurophysiology, Liverpool Hospital, NSW, Australia Mohammad Mahdi Parvizi Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran AND Persian Medicine Network (PMN), Universal Scientific Education and Research Network (USERN), Tehran, Iran AND Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Mohadeseh Ostovar Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 2023 06 07 2023 11 08 Sleep paralysis, described as Kabus in Persian medicine (PM), is a state during sleep in which a person senses heaviness on the chest without the ability to speak or move. This study aims to review sleep paralysis from the viewpoint of Persian medicine. Five original reference books on PM were reviewed and data about the definition, etiology, and clinical features of sleep paralysis were extracted. Two main etiologies have been mentioned: evaporation of vapor to the brain and brain dystemperament due to cold reaching the brain; both of which cause weakness and dysfunction of the brain. PM recommends low-cost and available remedies for sleep paralysis such as dietary modification, oral and topical herbal medications, and manual interventions like “Fasd” (phlebotomy). Recent studies have shown the neuroprotective effect of these herbal drugs which can improve cognition and memory. Further studies are needed to evaluate the efficacy of the recommended remedies for sleep paralysis. https://jtim.tums.ac.ir/index.php/jtim/article/view/1087