Traditional and Integrative Medicine <p><strong>Traditional and Integrative Medicine&nbsp;</strong>is an international quarterly&nbsp;open access peer-reviewed journal of School of Traditional Medicine published on behalf of Tehran University of Medical Sciences. This journal covering all scientific aspects of traditional, complementary and integrative medicines including history, chemistry, pharmacology, molecular mechanism, proteomics, genomics, metabolomics, safety, quality control, and clinical trial.&nbsp;Traditional and Integrative Medicine provides a bridge connected the tradition medicine system to the modern life science with the efforts of top scientists, as well as a resource to pursuit the solutions for the existing common issues in the traditional medicine. All type of studies including original researches, reviews, systematic reviews, meta-analyses, short communications, case reports, letters and editorials from the scientists in all over the worlds are welcome to this journal.</p> en-US <span>The <em>Traditional and Integrative Medicine</em> allow the author(s) to hold the copyright without restrictions. Also the journal allow the author(s) to retain publishing rights without restrictions.</span> (Dr. Roja Rahimi) (TUMS Journals Office) Mon, 01 Oct 2018 00:00:00 +0330 OJS 60 Assessment of Meta-Analysis/ Systematic Review on Acupuncture Therapy for post stroke depression (PSD) <p><strong>Abstract</strong></p> <p>A large number of studies have been conducted on the treatment of post-stroke depression with acupuncture. The purpose of this study was to review the published review literature about the efficacy of acupuncture for treating depression in stroke survivors. Electronic databases (PubMed/MEDLINE (National Library of Medicine), CENTRAL (the Cochrane Library), Google Scholar, Science Direct China Academic Journals Full-text Database (CNKI)), have been used for terms “meta-analysis, systematic review acupuncture OR electroacupuncture and Post stroke depression”. Out of 2302 studies, 2 systematic reviews covering 2525 participants were selected for analysis. <strong><em>RESULTS:</em></strong> The review articles included in this study was methodologically high qualified (OQAQ score ≥7 and AMSTAR score ≥9) and acupuncture can treat the post-stroke depression in comparison to the antidepressant with fewer side effects. <strong><em>CONCLUSIONS: </em></strong>Acupuncture may benefit the patients who are suffering from post-stroke depression but for a strong recommendation of clinical usage more high-quality studies needed.&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> Mina Mirahmadpour, Fang Bang-Jiang ##submission.copyrightStatement## Mon, 01 Oct 2018 09:12:06 +0330 Campanula latifola, Giant Bellflower; Ethno-botany, Phytochemical and Antioxidant Evaluation <p><em>Campanula latifolia</em> is a plant of Campanulaceae family, commonly known as Giant bellflower. <em>Campanula</em> genus is mentioned in Iranian medicine sources with various names such as kaff- e- Maryam and Gol-e-estekani. The aim of this study was to assay the different groups of chemical compounds and to investigate the antioxidant effects of ethanolic extract of aerial parts and root of this plant. After providing 70% alcoholic extract of aerial parts and root, qualitative tests were performed to evaluate anthocyanins, saponins, cardiac glycosides, flavonoids, tannins, sterols, triterpenoids, and alkaloids. Tests of antioxidant effects were evaluated by DPPH free radical scavenging effect and the content of phenolic compounds in the extracts using Folin-Ciocalteu method. Phytochemical studies indicate that there are compounds of cardiac glycoside, triterpene, and sterols. In the quantitative analysis of the compounds of the two plant extracts, the total amount of phenols were measured 0.053 and 0.037 (mg Gallic acid/g extract) in aerial parts and root extracts, respectively. The amount of IC50 of DPPH radical scavenging activity of the plant has also been 1163.636 μg / ml for the aerial parts extract and 1419.354 μg / ml for the root extract. Considering the results and the presence of cardiac glycosides, triterpenoids, and sterols, further phytochemical and pharmacological studies are suggested.</p> Seyed Reza Moosavi, Mohammad Reza Shams Ardekani, Mahdi Vazirian, Seyede Nargess Sadati Lamardi ##submission.copyrightStatement## Mon, 01 Oct 2018 00:00:00 +0330 The Role of Body Organs in Cardiac Health from the Viewpoint of Avicenna <p>Some symptoms of heart illness can be due to diseases originating from other organs. In Persian medicine (PM), this state is called <em>participatory heart diseases</em>. Current medical findings have found an&nbsp;important association between symptoms of psychiatric disorders and chest pain. Some of the other organs such as the lungs, liver, stomach, intestines and uterus have a proven effect on the heart. This relationship between the heart and other body organs has been considered by different ancient medical doctrines during a long historical period. In this article <em>participatory heart diseases</em> are explained from the viewpoint of Avicenna.</p> Fataneh Hashem-Dabaghian, Farshad Amini-Behbahani, Roshanak Ghods, Mahsima Abdoli ##submission.copyrightStatement## Mon, 01 Oct 2018 00:00:00 +0330 An Approach to Hair Loss and its Management in Persian Medicine <p>Hair loss is a common problem among more than half of the world's population. The present study aimed to review and assess the etiologies, symptoms and basics of its treatment according to Persian medicine (PM). The main PM books including &nbsp;the Canon of Medicine, Zakhireh Kharazmshahi, Moalejat-e Aghili, Exir-e A’zam, Teb-e Akbari and Makhzan al-adviyah were searched and the related content on hair loss have been extracted. According to PM textbooks, the causes of hair loss can be divided into four categories: skin and hair nutrition disorders (low quality and quantity of nutrients, basal metabolism disorder, circulation of nutrients and skin absorption), skin pore problems (dilation and obstruction), inflammation, and environmental damage. To differentiate the above causes, several symptoms such as hair strand diameters, greasy or dry hair, the scalp condition at the affected area and general symptoms such as weakness and exhaustion were considered. In modern medicine sources, several causes are mentioned to be involved in the process of hair loss including nutritional disorders and anemia, hormonal disorders like thyroid problems, genetics and environmental factors. Applying topical oils of Myrtle, Emblic myrobalan, Myrobalan, Acacia, Oak gall, Lotus, and Violet, as well as the mucilage of marshmallow, common mallow, Psyllium and also labdanum along with nutrition correction and consumption of nutritious foods such as almond, currant and walnut based on the type of hair loss have been recommended. Considering that the causes of hair loss in PM and modern medicine are similar, it seems that therapeutic recommendations of PM provide a suitable ground for future studies.</p> Narjes Gorji, Maryam Naeimi, Reihaneh Moeini, Zahra Memariani, Fatemeh Kolangi ##submission.copyrightStatement## Mon, 01 Oct 2018 00:00:00 +0330 Persian Medicine Recommendations in Reducing Mental Health Disorders due to Natural Disasters <p>Throughout history, human has experienced accident and natural disasters such as earthquakes and floods. One of the problems that people encounter after natural disasters is the spiritual and mental complications such as sadness and grief that are inevitable in accidents and disasters and inappropriate treatment leads to physical problems for individuals. The purpose of this study was to evaluate the role of Persian medicine in reducing the spiritual and mortal complications arising from natural disasters.</p> <p>The Persian medicine considers six essential principles (<em>seteyeh zarooriyeh</em>) for keeping health including climate (<em>Ab va Hava</em>), eating and drinking (<em>Khordan va Ashamidan</em>), sleep and wakefulness (<em>Khab va Bidari</em>), body movement and immobility (<em>Harkat va Sokon</em>), retention and excretion of materials (<em>Ehtebas va Estefragh</em>), spiritual and mental moods (<em>Aaraze nafsani</em>). Persian medicine has a special focus on spiritual and mental moods; because they can have a very quick and profound effect on the health of individuals. In the other words, sadness, fear and depression lead to reduction of the body strength and slowness of the refreshing process after natural disaster; while moderate happiness boosts the strengths and increase the life expectancy as well; and makes the work progress faster. Persian medicine scholars have suggested the medical treatments and non-pharmaceutical measures. Medical recommendations include the use of refreshing exhilarating (<em>mofarrehat</em>). One of the non-pharmaceutical measures for the survivors of critical accident to have an active spirit for resuming the life is using influence of the words power of the individuals trusted by the people. The views of Persian medicine scholars can be considered as a good way to improve the spiritual -mental states of injured people from natural disasters and to reduce their therapeutic costs. Conducting clinical studies is recommended in this regard.</p> Marzieh Qaraaty, Jale Aliasl, Malihe Tabarrai ##submission.copyrightStatement## Mon, 01 Oct 2018 00:00:00 +0330 A review on the chemical versus alternative treatments of Leukemia <p><strong>Common treatments for Leukemia, such as chemotherapy, have played a key role in the treatment of this life-threatening disease. However, they are associated with many side effects such as cardiovascular diseases, ocular diseases, lung toxicity, and endocrine dysfunction. The adverse effects of the common treatments are aggressive for elderly patients and patients who are unable to tolerate the treatments, resulting in their lower survival rate. Thus, more than ever before, Leukemia patients are now turning to complementary and alternative treatments. The objective of this study was to review recent literature to compare common and traditional treatments based on efficacy and associated side effects. Chemotherapy and radiation therapy are associated with many side effects, as is stem cell transplantation, which often accompanies these two treatments. Not many studies have been done on alternative, traditional treatments; however, a small number of studies showed that traditional medicine are effective in vitro. Thus, more scientific studies and clinical trials are needed to be done on alternative treatments to find the efficacy, potency and safety of their associated medicines and procedures. As medicinal concepts of the alternative, traditional treatments usually differ from the common medical treatments—although they both have the same curative goal—</strong><strong>greater research and communication between traditional medical researchers and practitioners in alternative therapeutic traditions may lead to new and effective medicine with fewer side effects.</strong></p> Aliya Fatima Mirza ##submission.copyrightStatement## Mon, 01 Oct 2018 13:59:34 +0330 A new strategy for treatment of chronic wounds according to Persian medicine: An evidence- based review <p><strong>Introduction</strong>: Chronic wounds reduce patient's quality of life by complications such as pain, secretions, and reduction of movement and impose large costs to health system. Thus, looking for treatment methods with higher success and less complications seems to be necessary. In Persian medicine, a variety of specific nutrients and medicinal plants have been recommended for chronic wounds. The aim of present study is to scientifically evaluate the nutrients and medicinal plants claimed to be effective for chronic wounds in Persian medicine.</p> <p><strong>Material and method:</strong> Nutrients and medicinal plants recommended for chronic wounds in Persian medicine have been extracted from corresponding literatures. The obtained items were individually searched in electronic databases to obtain any <em>in vitro</em>, animal, or clinical evidence of their efficacy and possible underlying mechanisms.</p> <p><strong>Results:</strong> The treatment of chronic wounds in Persian medicine consists of three steps .At first step some special foods like egg yolk and fig with special characteristics such as hematopoietic effect and antimicrobial activity are recommended. Administration of natural remedies in order to reduce internal inflammation and improve wound healing process such as <em>Crocus sativus</em> and <em>Aloe vera</em> consists of the second step. Finally the third step includes the use of topical natural agents that affects various stages of wound healing and can complete the wound healing process.</p> <p><strong>Conclusion:</strong> According to Persian medicine, administration nutrients and medicinal plants is prior to topical treatments for management of chronic wounds. This strategy provides a new approach for management of chronic wounds and seems to be more useful than conventional treatment which is mostly focused on topical treatment</p> laila Shirbeigi, soodeh karami, Mina Mohebbi, Fatemeh Nejatbakhsh, Roja Rahimi ##submission.copyrightStatement## Mon, 01 Oct 2018 14:08:41 +0330