Vitiligo and its Medicinal Plants from the Viewpoint of Iranian Traditional Medicine
AbstractVitiligo as a common depigmenting skin disorder plays a very important role in patient’s quality of life. It can cause serious emotional stress, which necessitates its treatment. Because of lack of desirable efficacy of conventional therapies, considering complementary therapies for the management of vitiligo is increasing. The aim of this article is to describe Iranian traditional medicine (ITM) approach to vitiligo mechanism and prognosis as well as medicinal plants proposed for the management of this disease. ITM believes human body organs consist of four fundamental humors. All of them are composed of very specific quantity and quality and any kind of diseases supposedly, is the result of excess or deficit of these humors. Changes in the quantity of “phlegm humor” and improper function of “expulsive faculty” are two main causes of vitiligo. In this paper, the vitiligo prognosis according to ITM and recommended herbal medicines according to the stage of disease have been explained.
Wong SM, Baba R. Quality of life among Malaysian patients with vitiligo. Int J Dermatol 2012; 51(2): 158-61.
Yaghoobi R, Omidian M, Bagherani N. Vitiligo: a review of the published work. J Dermatol 2011;38(5): 419-31.
Bilgic O, Bilgic A, Akis HK, Eskioglu F, Kilic EZ.Depression, anxiety and health-related quality of life in children and adolescents with vitiligo. Clin Exp Dermatol 2011; 36(4): 360-5.
van Geel N, Mollet I, Brochez L, Dutre M, de Schepper S, Verhaeghe E, et al. New insights in segmental vitiligo: case report and review of theories. Br J Dermatol 2012; 166(2): 240-6.
Ghafourian A, Ghafourian S, Sadeghifard N, Mohebi R, Shokoohini Y, Nezamoleslami S, et al. Vitiligo: symptoms, pathogenesis and treatment. Int J Immunopathol Pharmacol 2014; 27(4): 485-9.
Kim DY, Oh SH, Hann SK. Classification of segmental vitiligo on the face: clues for prognosis. Br J Dermatol 2011; 164(5): 1004-9.
Whitton ME, Pinart M, Batchelor J, Leonardi-Bee J, González U, Jiyad Z, et al. Treatments for vitiligo. The Cochrane Library 2015; (2): 1-4.
Jorjani E. Zakhireye Khwarazmshahi. Tehran, Iran: Cultural foundation of Iran; 1976. p. 60. [In Persian].
Avicenna. The canon of medicine. Beirut, Lebanon: Institute Alaalami Library; 2005. p. 41-6, 111-3.
Aghili Khorasani MH. Kholasat Al-Hekmah. Qom, Iran: Esmaeilian Publications; 2006. [In Persian].
Ahvazi AIA. Perfect creation in medicine (Kamel Alsana'e). Qom, Iran: Jalaleddin Publications;2009. [In Persian].
Arzani MA. Akbari's medicine (Teb Akbari).Qom, Iran: Jalaleddin Publications; 2009. [In Persian].
Azam Khan HM. The greatest elixir (Exir Azam).Tehran, Iran: Research Institute for Islamic and Complementary Medicine (RICM); 2009. [In Persian].
Kermani NIA. Explain of the causes and signs (Sharh Asbab va Alaem). Qom, Iran: Jalaleddin Publications; 2009. [In Persian].
Zakariya Al-Razi M. Al-Hawi. Beirut, Lebanon: Dare Ehya al Toras al Arabi; 2004.
Yan DM, Chang YX, Wang YF, Liu EW, Li J, Kang LY, et al. In vivo pharmacokinetics of bakuchiol after oral administration of bakuchiol extraction in rat plasma. J Ethnopharmacol 2010;128(3): 697-702.
Babitha S, Shin JH, Nguyen DH, Park SJ, Reyes GA, Caburian A, et al. A stimulatory effect of Cassia occidentalis on melanoblast differentiation and migration. Arch Dermatol Res 2011; 303(3):211-6.
Zhang X, Feng J, Mu K, Ma H, Niu X, Liu C, et al. Effects of single herbal drugs on adhesion and migration of melanocytes. J Tradit Chin Med 2005;25(3): 219-21.
Mou KH, Zhang XQ, Yu B, Zhang ZL, Feng J.Promoting of melanocyte adhesion and migration by Malytea Scurfpea fruit in vitro. Methods Find Exp Clin Pharmacol 2004; 26(3): 167-70.
Lin Z, Hoult JR, Bennett DC, Raman A.Stimulation of mouse melanocyte proliferation by Piper nigrum fruit extract and its main alkaloid, piperine. Planta Med 1999; 65(7): 600-3.